Papers with Impact Factor > 10

• H. Mohsenin, J. Pacheco, S. Kemmer, H.J. Wagner, N. Höfflin, T. Bergmann, T. Baumann, C. Jerez-Longres, A. Ripp, N. Jork, H.J. Jessen, M. Fussenegger, M. Köhn, J. Timmer, W. Weber
  PenTag, a versatile platform for synthesizing protein-polymer biohybrid materials. Advanced Functional Materials , 2023,

• A.J. Riesle, M. Gao, M. Rosenblatt, J. Hermes, H. Hass, A. Gebhard, M. Veil, B. Grüning, J. Timmer, D. Onichtchouk.
  Activator-blocker model of transcriptional regulation by pioneer-like factors. Nature Communications 14 , 2023, 5677

• C. Jerez-Longres, M. Gomez-Matos, J. Becker, M. Hörner, F.-G. Wieland, J. Timmer, W. Weber.
  Engineering a material-genetic interface as safety switch for embedded therapeutic cells. Biomaterials Advances , 2023,

• M. Gao, M. Veil, M. Rosenblatt, A.J. Riesle, A. Gebhard, H. Hass, L. Buryanova, L.Y. Yampolsky, B. Grüning, J. Timmer, D. Onichtchouk.
  Pluripotency factors determine gene expression repertoire at zygotic genome activation. Nature Communications 13, 2022, 788

• N. Schneider, F.-G. Wieland, D. Kong, A.A.M. Fischer, M. Hörner, J. Timmer, H. Ye, W. Weber.
  Liquid-liquid phase separation of light-inducible transcription factors increases transcription activation in mammalian cells and mice. Science Advances 7, 2021, eabd3568

• R. Ochoa-Fernandez, N.B. Abel, F.-G. Wieland, J. Schlegel, L.A. Koch, B. Miller, R. Engesser, G. Giuriani, S.M. Brandl, J. Timmer, W. Weber, T. Ott, R. Simon, M.D. Zurbriggen.
  PULSE: Optogenetic control of gene expression in plants insensitive to ambient light. Nature Methods 17, 2020, 717-725

• M. Hörner, K. Raute, B. Hummel, J. Madl, G. Creusen, O.S. Thomas, E.H. Christen, N. Hotz, R.J. Gübeli, R. Engesser, B. Rebmann, J. Lauer, B. Rolauffs, J. Timmer, W.W.A. Schamel, J. Pruszak, W. Römer, M.D. Zurbriggen, Ch. Friedrich, A. Walther, S. Minguet, R. Sawarkar, W. Weber.
  Phytochrome-based extracellular matrix with reversibly tunable mechanical properties. Advanced Materials 11, 2019, 1806727

• H.J. Wagner, S. Kemmer, R. Engesser, J. Timmer, W. Weber.
  Biofunctionalized materials featuring feedforward and feedback circuits exemplified by the detection of Botulinum Toxin A. Advanced Science 6, 2019, 1801320
  Cover page

• H.J. Wagner, R. Engesser, K. Ermes, C. Geraths, J. Timmer, W. Weber.
  Synthetic biology-inspired design of signal-amplifying materials systems. Materials Today 22, 2019, 25-34

• H.M. Beyer, R. Engesser, M. Hörner, J. Koschmieder, P. Beyer, J. Timmer, M.D. Zurbriggen, W. Weber.
  Synthetic Biology makes Polymer Materials count. Advanced Materials, 2018, 1800472

• L. Adlung, S. Kar, M.-C. Wagner, B. She, S. Chakraborty, J. Bao, S. Lattermann, M. Boerries, H. Busch, P. Wuchter, A.D. Ho, J. Timmer, M. Schilling, T. Höfer, U. Klingmüller.
  Protein abundance pattern of AKT and ERK pathway components governs cell-type-specific regulation of proliferation. Molecular Systems Biology 13, 2017, 904

• T. Goldmann, N. Zeller, J. Raasch, K. Kierdorf, K. Frenzel, L. Ketscher, A. Basters, O. Staszewski, S.M. Brendecke, A. Spiess, T.L. Tay, C. Kreutz, J. Timmer, G.M. Mancini, T. Blank, G. Fritz, K. Biber, R. Lang, D. Malo, D. Merkler, M. Heikenwälder, K.P. Knobeloch, M. Prinz.
  USP18 lack in microglia causes destructive interferonopathy of the mouse brain. EMBO Journal 34, 2015, 1612-1629
  See also here

• J. Rausenberger, A. Tscheuschler, W. Nordmeier, F. Wüst, J. Timmer, E. Schäfer, Ch. Fleck, A. Hiltbrunner.
  Photoconversion and nuclear trafficking cycles determine phytochrome A's response profile to far-red light. Cell 146, 2011, 813-825
  Supplementary Information

• P. Christopoulos, D. Pfeifer, K. Bartholome, M. Follo, J. Timmer, P. Fisch, H. Veelken.
  Definition and characterization of the systemic T-cell dysregulation in untreated indolent B cell lymphoma and very early CLL. Blood 117, 2011, 3836-3846

• S. Zellmer, W. Schmidt-Heck, A. Bauer, C. Meyer, T. Lehmann, T. Sparna, P. Godoy, J. Amin, W. Schormann, E. Bedawy, S. Hammad, C. Kern, C. Kreutz, J. Timmer, G. Walz, F. von Weizsäcker, P.A. Thürmann, S. Dooley, I. Merfort, R. Guthke, J.G. Hengstler, R. Gebhardt.
  The transcription factors ETF, E2F and SP-1 are involved in cytokine-independent proliferation of murine hepatocytes. Hepatology 52, 2010, 2127-2136

• V. Becker, M. Schilling, J. Bachmann, U. Baumann, A. Raue, T. Maiwald, J. Timmer, U. Klingmüller.
  Covering a broad dynamic range: Information processing at the erythropoietin receptor. Science 328, 2010, 1404-1408
  Supplementary Information
  Data and models of the paper

• M. Schilling, T. Maiwald, S. Hengl, D. Winter, C. Kreutz, W. Kolch, W.D. Lehmann, J. Timmer, U. Klingmüller.
  Theoretical and experimental analysis links isoform-specific ERK signalling to cell fate decisions. Molecular Systems Biology 5, 2009, 334
  Supplementary Information
  Data analyzed in the paper
  SBML-file of the model

• N. Borisov, E. Aksamitiene, A. Kiyatkin, S. Legewie, J. Berkhout, T. Maiwald, N.P. Kaimachnikov, J. Timmer, J.B. Hoek, B.N. Kholodenko.
  Systems-level interactions between insulin-EGF networks amplify mitogenic signaling. Mol. Sys. Bio. 5, 2009, 256

• S. Digiuni, S. Schellmann, F. Geier, B. Greese, M. Pesch. K. Wester, B. Dartan, V. Mach, B. P. Srinivas, J. Timmer, C. Fleck, M. Hülskamp.
  A competitive complex formation mechanism underlies trichome patterning on Arabidopsis leaves. Mol. Sys. Bio. 4, 2008, 217
  

• D. Bouyer, F. Geier, F. Kragler, A. Schnittger, M. Pesch, K. Wester, R. Balkunde, J. Timmer, C. Fleck, M. Hülskamp.
  Two-dimensional patterning by a trapping/depletion mechanism: The role of TTG1 and GL3 in Arabidopsis trichome formation. PLoS Biology 6, 2008, e141

• E. Anastasiou, S. Kenz, M. Gerstung, D. MacLean, J. Timmer, C. Fleck, M. Lenhard.
  Control of plant organ size by KLUH/CYP78A5-dependent intracellular signalling. Developmental Cell 13, 2007, 843-856

• Pfeifer D., Pantic M., Skatulla I., Rawluk J., Kreutz C., Martens U., Fisch P., Timmer J., Veelken H.
  Genome-wide analysis of DNA copy number changes in CLL using high-density SNP arrays. Blood 109, 2007, 1202-1210

• Sick S., Reinker S., Timmer J., Schlake T.
  WNT and DKK determine hair follicle spacing through a reaction-diffusion mechanism. Science 314, 2006, 1447-1450
  Supplementary Information
  Perspective
  Preview in Cell

• Fang X., Zeisel M.B., Wilpert J., Gissler B., Thimme R., Kreutz C., Maiwald T., Timmer J., Kern W.V., Donauer J., Geyer M., Walz G., Delpa E., von Weizsäcker F., Blum H.E., Baumert T.F.
  Host cell responses induced by Hepatitis C virus binding. Hepatology 43, 2006, 1326-1336

• Kollmann M., Bartholome K., Lovdok L., Timmer J., Sourjik V.
  Design principles of a bacterial signalling network. Nature 438, 2005, 504-507
  Supplementary Information

• Swameye I., Müller T.G., Timmer J., Sandra O., Klingmüller U.
  Identification of nucleocytoplasmic cycling as a remote sensor in cellular signaling by data-based modeling. Proc. Natl. Acad. Sci. 100, 2003, 1028-1033.
  Supplementary Information
  Data analyzed in the paper

• Hellwig B., Häußler S., Schelter B., Lauk M., Guschlbauer B., Timmer J., Lücking C.H.
  Tremor-correlated cortical activity in essential tremor. The Lancet 357, 2001, 519-523